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Recombinant Human SERTA domain-containing protein 2 (SERTAD2)

ACP18262

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Specifications

Cat.No	ACP18262	Target Name	SERTAD2
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-314	Protein Length	Full length protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q14140

Background Information

Uniprot Id

Q14140
Target Species

Human
Target Name

SERTAD2
Target Full Name

SERTA domain-containing protein 2
Target Function

Acts at E2F-responsive promoters as coregulator to integrate signals provided by PHD- and/or bromodomain-containing transcription factors. May act as coactivator as well as corepressor of E2F1-TFDP1 and E2F4-TFDP1 complexes on E2F consensus binding sites, which would activate or inhibit E2F-target genes expression. Modulates fat storage by down-regulating the expression of key genes involved in adipocyte lipolysis, thermogenesis and oxidative metabolism.
Target Subcellular Location

Nucleus. Cytoplasm. Note=Exported out of the nucleus via its NES in a XPO1-dependent manner. Once in the cytoplasm, is degraded by the proteasome.
Target Tissue Specificity

Expressed in adipose tissue.
Target Synonyms

KIAA0127; MGC126688; MGC126690; Sei 2; Sei-2; Sei2; SERTA domain containing 2; SERTA domain-containing protein 2; SERTAD2; SRTD2_HUMAN; Transcriptional regulator interacting with the PHD bromodomain 2; Transcriptional regulator interacting with the PHD-bromodomain 2; Transcriptional regulator interacting with the PHS-bromodomain 2; TRIP Br2; TRIP-Br2

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Recombinant Human SERTA domain-containing protein 2 (SERTAD2)

Specifications

Immunogen Information

Inquire Recombinant Human SERTA domain-containing protein 2 (SERTAD2) Now

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