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Recombinant Human SH3 and cysteine-rich domain-containing protein 3 (STAC3)

ACP14061

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Specifications

Cat.No	ACP14061	Target Name	STAC3
Target Synonyms	MGC2793; SH3 and cysteine rich domain 3; SH3 and cysteine rich domain-containing protein 3; SH3 and cysteine-rich domain-containing protein 3; stac3; STAC3_HUMAN	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-364
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q96MF2

Background Information

Uniprot Id

Q96MF2
Target Species

Human
Target Name

STAC3
Target Full Name

SH3 and cysteine-rich domain-containing protein 3
Target Function

Required for normal excitation-contraction coupling in skeletal muscle and for normal muscle contraction in response to membrane depolarization. Required for normal Ca(2+) release from the sarcplasmic reticulum, which ultimately leads to muscle contraction. Probably functions via its effects on muscle calcium channels. Increases CACNA1S channel activity, in addition to its role in enhancing the expression of CACNA1S at the cell membrane. Has a redundant role in promoting the expression of the calcium channel CACNA1S at the cell membrane. Slows down the inactivation rate of the calcium channel CACNA1C.
Target Involvement

Native American myopathy (NAM)
Target Subcellular Location

Cytoplasm. Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cell membrane, sarcolemma, T-tubule.
Target Synonyms

MGC2793; SH3 and cysteine rich domain 3; SH3 and cysteine rich domain-containing protein 3; SH3 and cysteine-rich domain-containing protein 3; stac3; STAC3_HUMAN

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Recombinant Human SH3 and cysteine-rich domain-containing protein 3 (STAC3)

Specifications

Immunogen Information

Inquire Recombinant Human SH3 and cysteine-rich domain-containing protein 3 (STAC3) Now

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