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| Cat.No | ACP06369 | Target Name | ST8SIA3 |
|---|---|---|---|
| Target Synonyms | 3-Gal-beta-1, 4-GlcNAc-R:alpha 2, 8-sialyltransferase 3; Sialyltransferase 8C; SIAT8-C; Sialyltransferase St8Sia III; ST8SiaIII, 8-sialyltransferase 8C; Alpha-2, 8-sialyltransferase III; ST8 alpha-N-acetyl-neuraminide alpha-2, 8-sialyltransferase; Alpha-2, ST8SIA3; SIAT8C; Sia-alpha-2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O43173 |
|---|
Uniprot Id
O43173
Target Species
Human
Target Name
ST8SIA3
Target Full Name
Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase ST8SIA3
Target Function
Catalyzes the transfer of sialic acid from a CMP-linked sialic acid donor onto the terminal sialic acid of an acceptor through alpha-2,8-linkages. Is active with alpha-2,3-linked, alpha-2,6-linked and alpha-2,8-linked sialic acid of N-linked oligosaccharides of glycoproteins and glycolipids. Displays preference for substrates with alpha-2,3-linked terminal sialic acid. It can form polysialic acid in vitro directly on alpha-2,3-, alpha-2,6-, or alpha-2,8-linked sialic acid.
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Target Protein Families
Glycosyltransferase 29 family
Target Tissue Specificity
Expressed in fetal and adult brain and fetal liver.
Target Synonyms
ST8SIA3; SIAT8C; Sia-alpha-2,3-Gal-beta-1,4-GlcNAc-R:alpha 2,8-sialyltransferase; Alpha-2,8-sialyltransferase 8C; Alpha-2,8-sialyltransferase III; ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3; Sialyltransferase 8C; SIAT8-C; Sialyltransferase St8Sia III; ST8SiaIII
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