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Recombinant Human Sigma intracellular receptor 2 (TMEM97), Truncated

ACP08620

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP08620 Target NameTMEM97
Target SynonymsTMEM97; MAC30; S2R; Sigma intracellular receptor 2; Sigma-2 receptor; Sigma2 receptor; Meningioma-associated protein 30; Transmembrane protein 97FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ5BJF2
Background Information
  • Uniprot Id

    Q5BJF2

  • Target Species

    Human

  • Target Name

    TMEM97

  • Target Full Name

    Sigma intracellular receptor 2

  • Target Function

    Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cancer cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. Under investigation for its potential diagnostic and therapeutic uses. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.

  • Target Subcellular Location

    Nucleus membrane; Multi-pass membrane protein. Rough endoplasmic reticulum membrane; Multi-pass membrane protein.

  • Target Protein Families

    TMEM97/sigma-2 receptor family

  • Target Tissue Specificity

    Widely expressed in normal tissues. Expressed in pancreatic, renal, breast, colon, ovarian surface epithelial (OSE) cells. Highly expressed in various proliferating cancer cells.

  • Target Synonyms

    TMEM97; MAC30; S2R; Sigma intracellular receptor 2; Sigma-2 receptor; Sigma2 receptor; Meningioma-associated protein 30; Transmembrane protein 97

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