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Recombinant Human Signal recognition particle 54 kDa protein (SRP54)

ACP00216

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Specifications

Cat.No	ACP00216	Target Name	SRP54
Target Synonyms	SRP54	Form	Liquid or Lyophilized powder
Expression System	E.coli	Expression Range	1-504aa
Mol Weight	63.2 kDa	Protein Length	Full length
Purity	Greater than 85% as determined by SDS-PAGE.	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P61011

Background Information

Uniprot Id

P61011
Target Species

Human
Target Name

SRP54
Target Full Name

Signal recognition particle subunit SRP54
Target Function

Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein). Plays a role in proliferation and differentiation of granulocytic cells, neutrophils migration capacity and exocrine pancreas development.
Target Subcellular Location

Nucleus speckle. Cytoplasm. Endoplasmic reticulum.
Target Protein Families

GTP-binding SRP family, SRP54 subfamily
Target Research Area

Signal Transduction
Target Synonyms

Signal recognition particle 54 kDa protein; Signal recognition particle 54kDa; SRP 54; SRP54; SRP54_HUMAN
Target Background

Enables several functions, including 7S RNA binding activity; endoplasmic reticulum signal peptide binding activity; and guanyl ribonucleotide binding activity. Contributes to GTPase activity. Involved in granulocyte differentiation and protein targeting to ER. Located in cytosol and nucleus. Part of signal recognition particle, endoplasmic reticulum targeting. Implicated in severe congenital neutropenia 8.

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Recombinant Human Signal recognition particle 54 kDa protein (SRP54)

Specifications

Immunogen Information

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