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| Cat.No | ACP21145 | Target Name | SERF1A |
|---|---|---|---|
| Target Synonyms | SERF1A; FAM2A; SERF1; SMAM1;; SERF1B; FAM2B; SERF1; SMAM1; Small EDRK-rich factor 1; Protein 4F5; h4F5; SMA modifier 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-110 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O75920 |
|---|
Uniprot Id
O75920
Target Species
Human
Target Name
SERF1A
Target Full Name
Small EDRK-rich factor 1
Target Function
Positive regulator of amyloid protein aggregation and proteotoxicity. Induces conformational changes in amyloid proteins, such as APP, HTT, and SNCA, driving them into compact formations preceding the formation of aggregates.
Target Subcellular Location
Cytoplasm, cytosol. Nucleus.
Target Protein Families
SERF family
Target Tissue Specificity
Isoform Long is predominantly expressed in heart, brain and skeletal muscle. Isoform Short and Isoform Long are expressed throughout the central nervous system, including spinal cord.
Target Synonyms
SERF1A; FAM2A; SERF1; SMAM1;; SERF1B; FAM2B; SERF1; SMAM1; Small EDRK-rich factor 1; Protein 4F5; h4F5; SMA modifier 1
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