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Recombinant Human Sodium-dependent neutral amino acid transporter B (0)AT1 (SLC6A19), Truncated

ACP06101

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Specifications

Cat.No	ACP06101	Target Name	SLC6A19
Target Synonyms	SLC6A19; B0AT1; Sodium-dependent neutral amino acid transporter B(0)AT1; Solute carrier family 6 member 19; System B(0) neutral amino acid transporter AT1	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q695T7

Background Information

Uniprot Id

Q695T7
Target Species

Human
Target Name

SLC6A19
Target Full Name

Sodium-dependent neutral amino acid transporter B(0)AT1
Target Function

Transporter that mediates resorption of neutral amino acids across the apical membrane of renal and intestinal epithelial cells. This uptake is sodium-dependent and chloride-independent. Requires CLTRN in kidney or ACE2 in intestine for cell surface expression and amino acid transporter activity.
Target Involvement

Hartnup disorder (HND); Hyperglycinuria (HG); Iminoglycinuria (IG)
Target Subcellular Location

Cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein.
Target Protein Families

Sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family, SLC6A19 subfamily
Target Tissue Specificity

Robust expression in kidney and small intestine, with minimal expression in pancreas. Also expressed in stomach, liver, duodenum, ileocecum, colon and prostate. Not detected in testis, whole brain, cerebellum, fetal liver, spleen, skeletal muscle, uterus,
Target Synonyms

SLC6A19; B0AT1; Sodium-dependent neutral amino acid transporter B(0)AT1; Solute carrier family 6 member 19; System B(0) neutral amino acid transporter AT1

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Recombinant Human Sodium-dependent neutral amino acid transporter B (0)AT1 (SLC6A19), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Sodium-dependent neutral amino acid transporter B (0)AT1 (SLC6A19), Truncated Now

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