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| Cat.No | ACP05412 | Target Name | SLC17A3 |
|---|---|---|---|
| Target Synonyms | SLC17A3; NPT4; Sodium-dependent phosphate transport protein 4; Na(+)/PI cotransporter 4; Sodium/phosphate cotransporter 4; Solute carrier family 17 member 3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O00476 |
|---|
Uniprot Id
O00476
Target Species
Human
Target Name
SLC17A3
Target Full Name
Sodium-dependent phosphate transport protein 4
Target Function
voltage-driven, multispecific, organic anion transporter able to transport para-aminohippurate (PAH), estrone sulfate, estradiol-17-beta-glucuronide, bumetanide, and ochratoxin A. Isoform 2 functions as urate efflux transporter on the apical side of renal proximal tubule and is likely to act as an exit path for organic anionic drugs as well as urate in vivo. May be involved in actively transporting phosphate into cells via Na(+) cotransport.
Target Subcellular Location
[Isoform 1]: Endoplasmic reticulum membrane; Multi-pass membrane protein.; [Isoform 2]: Cell membrane; Multi-pass membrane protein.
Target Protein Families
Major facilitator superfamily, Sodium/anion cotransporter family
Target Tissue Specificity
Expressed in the liver and kidney. It is detected in proximal tubules in renal cortex as well as some tubules and glomeruli, with highest expression at the apical side of proximal tubules (at protein level).
Target Synonyms
SLC17A3; NPT4; Sodium-dependent phosphate transport protein 4; Na(+)/PI cotransporter 4; Sodium/phosphate cotransporter 4; Solute carrier family 17 member 3
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