Recombinant Human Solute carrier family 15 member 1 (SLC15A1), Truncated

Uniprot Id

P46059

Target Species

Human

Target Name

SLC15A1

Target Full Name

Solute carrier family 15 member 1

Target Function

Proton-coupled amino-acid transporter that transports oligopeptides of 2 to 4 amino acids with a preference for dipeptides. Primarily responsible for the absorption of dietary di- and tripeptides from the small intestinal lumen.

Target Subcellular Location

Membrane; Multi-pass membrane protein.

Target Protein Families

PTR2/POT transporter (TC 2.A.17) family

Target Synonyms

+peptide cotransporter; HPECT1; HPEPT1; Human peptide transporter (HPEPT1) mRNA complete cds; Intestinal H; Intestinal H(+)/peptide cotransporter; Oligopeptide transporter; Oligopeptide transporter small intestine isoform; PEPT1; Peptide transporter 1; S15A1_HUMAN; Slc15a1; small intestine isoform; Solute carrier family 15 (oligopeptide transporter) member 1; Solute carrier family 15 member 1

Target Background

This gene encodes an intestinal hydrogen peptide cotransporter that is a member of the solute carrier family 15. The encoded protein is localized to the brush border membrane of the intestinal epithelium and mediates the uptake of di- and tripeptides from the lumen into the enterocytes. This protein plays an important role in the uptake and digestion of dietary proteins. This protein also facilitates the absorption of numerous peptidomimetic drugs.