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| Cat.No | ACP05604 | Target Name | SLC22A14 |
|---|---|---|---|
| Target Synonyms | SLC22A14; OCTL2; ORCTL4; Solute carrier family 22 member 14; Organic cation transporter-like 4; ORCTL-4 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9Y267 |
|---|
Uniprot Id
Q9Y267
Target Species
Human
Target Name
SLC22A14
Target Full Name
Solute carrier family 22 member 14
Target Function
Riboflavin transporter localized at the inner mitochondrial membrane of the spermatozoa midpiece, which is required for male fertility. SLC22A14-mediated riboflavin transport is essential for spermatozoa energy generation and motility: riboflavin is the precursor of FMN and FAD, which are coenzymes of many enzymes in the TCA cycle (the citric acid cycle) in mitochondria. Required for sperm motility and normal sperm flagellar structure.
Target Subcellular Location
Mitochondrion inner membrane; Multi-pass membrane protein. Cell projection, cilium, flagellum membrane; Multi-pass membrane protein.
Target Protein Families
Major facilitator (TC 2.A.1) superfamily, Organic cation transporter (TC 2.A.1.19) family
Target Tissue Specificity
Ubiquitous.
Target Synonyms
SLC22A14; OCTL2; ORCTL4; Solute carrier family 22 member 14; Organic cation transporter-like 4; ORCTL-4
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