-
Chinese (Simplified)
-
English
-
German
-
Korean
-
Spanish
Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
| Cat.No | ACP05702 | Target Name | SLCO1B3 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NPD5 |
|---|
Uniprot Id
Q9NPD5
Target Species
Human
Target Name
SLCO1B3
Target Full Name
Solute carrier organic anion transporter family member 1B3
Target Function
Mediates the Na(+)-independent uptake of organic anions such as 17-beta-glucuronosyl estradiol, taurocholate, triiodothyronine (T3), leukotriene C4, dehydroepiandrosterone sulfate (DHEAS), methotrexate and sulfobromophthalein (BSP). Involved in the clearance of bile acids and organic anions from the liver.
Target Involvement
Hyperbilirubinemia, Rotor type (HBLRR)
Target Subcellular Location
Basolateral cell membrane; Multi-pass membrane protein.
Target Protein Families
Organo anion transporter (TC 2.A.60) family
Target Tissue Specificity
Highly expressed in liver, in particular at the basolateral membrane of hepatocytes near the central vein. Not detected in other tissues. Highly expressed in some cancer cell lines derived from colon, pancreas, liver and gall bladder.
Target Synonyms
HBLRR; Liver-specific organic anion transporter 2; LST-2; LST-3TM13; LST3; OATP-8; OATP1B3; Organic anion transporter 8; Organic anion-transporting polypeptide 8; SLC21A8; SLCO1B3; SO1B3_HUMAN; Solute carrier family 21 member 8; Solute carrier organic anion transporter family member 1B3
Notification