Recombinant Human Solute carrier organic anion transporter family member 3A1 (SLCO3A1), Truncated

Uniprot Id

Q9UIG8

Target Species

Human

Target Name

SLCO3A1

Target Full Name

Solute carrier organic anion transporter family member 3A1

Target Function

Mediates the Na(+)-independent transport of organic anions such as estrone-3-sulfate. Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin, but not DPDPE (a derivative of enkephalin lacking an N-terminal tyrosine residue), estrone-3-sulfate, taurocholate, digoxin nor DHEAS.

Target Subcellular Location

Cell membrane; Multi-pass membrane protein.

Target Protein Families

Organo anion transporter (TC 2.A.60) family

Target Tissue Specificity

Ubiquitous. Highly expressed in spleen and leukocytes. Generally the expression of isoform 1 is higher than that of isoform 2. Isoform 2 is particularly abundant in testis and brain. In testis, isoform 1 is detected in spermatogonia at different stages an

Target Synonyms

SLCO3A1; OATP3A1; OATPD; SLC21A11; Solute carrier organic anion transporter family member 3A1; OATP3A1; Organic anion transporter polypeptide-related protein 3; OATP-RP3; OATPRP3; Organic anion-transporting polypeptide D; OATP-D; PGE1 transporter; Sodium-independent organic anion transporter D; Solute carrier family 21 member 11

Target Background

Predicted to enable sodium-independent organic anion transmembrane transporter activity. Involved in positive regulation of NF-kappaB transcription factor activity; positive regulation of protein phosphorylation; and prostaglandin transport. Located in plasma membrane.