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| Cat.No | ACP19608 | Target Name | SPOPL |
|---|---|---|---|
| Target Synonyms | SPOPL; Speckle-type POZ protein-like; HIB homolog 2; Roadkill homolog 2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-392 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6IQ16 |
|---|
Uniprot Id
Q6IQ16
Target Species
Human
Target Name
SPOPL
Target Full Name
Speckle-type POZ protein-like
Target Function
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins, but with relatively low efficiency. Cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes containing homodimeric SPOPL or the heterodimer formed by SPOP and SPOPL are less efficient than ubiquitin ligase complexes containing only SPOP. May function to down-regulate the activity of cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complexes that contain SPOP.
Target Subcellular Location
Nucleus.
Target Protein Families
Tdpoz family
Target Synonyms
SPOPL; Speckle-type POZ protein-like; HIB homolog 2; Roadkill homolog 2
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