Home Products Recombinant Human Spindle and kinetochore-associated protein 3 (SKA3)

Recombinant Human Spindle and kinetochore-associated protein 3 (SKA3)

ACP14981

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Specifications

Cat.No	ACP14981	Target Name	SKA3
Target Synonyms	C13orf3; RAMA1; SKA3; SKA3_HUMAN; Spindle and kinetochore associated complex subunit 3; Spindle and kinetochore-associated protein 3	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-412
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q8IX90

Background Information

Uniprot Id

Q8IX90
Target Species

Human
Target Name

SKA3
Target Full Name

Spindle and kinetochore-associated protein 3
Target Function

Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the microtubule-stimulated oligomerization. Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules.
Target Subcellular Location

Cytoplasm, cytoskeleton, spindle. Chromosome, centromere, kinetochore.
Target Protein Families

SKA3 family
Target Synonyms

C13orf3; RAMA1; SKA3; SKA3_HUMAN; Spindle and kinetochore associated complex subunit 3; Spindle and kinetochore-associated protein 3

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Recombinant Human Spindle and kinetochore-associated protein 3 (SKA3)

Specifications

Immunogen Information

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