Recombinant Human Splicing factor U2AF 26 kDa subunit (U2AF1L4)

Cat.No	ACP14197	Target Name	U2AF1L4
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	1-202	Protein Length	Full Length of Isoform 2
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP14197

Target Name

U2AF1L4

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

1-202

Protein Length

Full Length of Isoform 2

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q8WU68

Background Information

Uniprot Id

Q8WU68
Target Species

Human
Target Name

U2AF1L4
Target Full Name

Splicing factor U2AF 26 kDa subunit
Target Function

RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T-cell activation; an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site. Shows a preference for AGC or AGA.
Target Subcellular Location

Nucleus. Nucleus speckle. Cytoplasm.
Target Protein Families

Splicing factor SR family
Target Tissue Specificity

Isoform 2 is widely expressed. Isoform 3 is highly expressed in heart, brain and lung, lower expressed in thymus and much lower expressed in peripheral blood leukocytes.
Target Research Area

others
Target Synonyms

FLJ35525; MGC33901; Splicing factor U2AF 26 kDa subunit; U2 auxiliary factor 26; U2 small nuclear RNA auxiliary factor 1 like 3; U2 small nuclear RNA auxiliary factor 1 like 4; U2 small nuclear RNA auxiliary factor 1 like protein 3; U2 small nuclear RNA auxiliary factor 1 like protein 4; U2 small nuclear RNA auxiliary factor 1-like protein 3; U2 small nuclear RNA auxiliary factor 1-like protein 4; U2(RNU2) small nuclear RNA auxiliary factor 1 like 3; U2(RNU2) small nuclear RNA auxiliary factor 1-like protein 3; U2AF1 like protein 3; U2AF1 RS3; U2AF1-like protein 3; U2AF1L3V1; U2AF1L4; U2AF1RS3; U2af26; U2AF4_HUMAN; U2RNU2 small nuclear RNA auxiliary factor 1 like 3; U2RNU2 small nuclear RNA auxiliary factor 1 like protein 3

Recombinant Human Splicing factor U2AF 26 kDa subunit (U2AF1L4)

Specifications

Immunogen Information

Inquire Recombinant Human Splicing factor U2AF 26 kDa subunit (U2AF1L4) Now

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