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Recombinant Human Spondin-2 (SPON2)

ACP11354

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP11354 Target NameSPON2
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range27-331Protein LengthFull Length of Mature Protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9BUD6
Background Information
  • Uniprot Id

    Q9BUD6

  • Target Species

    Human

  • Target Name

    SPON2

  • Target Full Name

    Spondin-2

  • Target Function

    Cell adhesion protein that promotes adhesion and outgrowth of hippocampal embryonic neurons. Binds directly to bacteria and their components and functions as an opsonin for macrophage phagocytosis of bacteria. Essential in the initiation of the innate immune response and represents a unique pattern-recognition molecule in the ECM for microbial pathogens. Binds bacterial lipopolysaccharide (LPS).

  • Target Subcellular Location

    Secreted, extracellular space, extracellular matrix.

  • Target Tissue Specificity

    Expressed in normal lung tissue but not in lung carcinoma cell lines.

  • Target Synonyms

    Differentially expressed in cancerous and non-cancerous lung cells 1; DIL 1; DIL-1; DIL1; DKFZp686G21139; FLJ16313; FLJ22401; FLJ34460; M spondin; Mindin; ORF Names: ; SPON 2; Spon2; SPON2_HUMAN; Spondin 2; Spondin 2 extracellular matrix protein; Spondin-2

  • Target Background

    Predicted to enable antigen binding activity; lipopolysaccharide binding activity; and metal ion binding activity. Predicted to be involved in cell adhesion. Predicted to act upstream of or within several processes, including defense response to other organism; opsonization; and positive regulation of cytokine production. Located in extracellular exosome.

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