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Recombinant Human Stromelysin-3 (MMP11)

ACP23490

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Specifications

Cat.No	ACP23490	Target Name	MMP11
Target Synonyms	Matrix Metalloproteinase 11; Matrix metalloproteinase-11; MMP-11; Mmp11; MMP11_HUMAN; SL 3; SL-3; SL3; ST3; STMY3; Stromelysin 3; Stromelysin III; Stromelysin-3	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	98-488
Protein Length	Full Length of Mature Protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P24347

Background Information

Uniprot Id

P24347
Target Species

Human
Target Name

MMP11
Target Full Name

Stromelysin-3
Target Function

May play an important role in the progression of epithelial malignancies.
Target Subcellular Location

Secreted, extracellular space, extracellular matrix.
Target Protein Families

Peptidase M10A family
Target Tissue Specificity

Specifically expressed in stromal cells of breast carcinomas.
Target Synonyms

Matrix Metalloproteinase 11; Matrix metalloproteinase-11; MMP-11; Mmp11; MMP11_HUMAN; SL 3; SL-3; SL3; ST3; STMY3; Stromelysin 3; Stromelysin III; Stromelysin-3
Target Background

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's, this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix.

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Recombinant Human Stromelysin-3 (MMP11)

Specifications

Immunogen Information

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