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| Cat.No | ACP12438 | Target Name | SLX1A |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-275 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BQ83 |
|---|
Uniprot Id
Q9BQ83
Target Species
Human
Target Name
SLX1A
Target Full Name
Structure-specific endonuclease subunit SLX1
Target Function
Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.
Target Subcellular Location
Nucleus.
Target Protein Families
SLX1 family
Target Synonyms
GIY YIG domain containing protein 1; GIY-YIG domain-containing protein 1; GIYD 1; GIYD 2; GIYD1; GIYD2; SLX 1; SLX1; SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae); SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae); SLX1_HUMAN; SLX1A; Slx1b; structure specific endonuclease subunit SLX1; Structure-specific endonuclease subunit SLX1
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