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| Cat.No | ACP03890 | Target Name | SUOX |
|---|---|---|---|
| Target Synonyms | EC 1.8.3.1; mitochondrial; Sulfite oxidase; Sulfite oxidase mitochondrial ; Sulfite oxidase; mitochondrial precursor; Suox; SUOX_HUMAN | Form | Liquid or Lyophilized powder |
| Expression System | Yeast | Expression Range | 80-545aa |
| Mol Weight | 53.6kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P51687 |
|---|
Uniprot Id
P51687
Target Species
Human
Target Name
SUOX
Target Full Name
Sulfite oxidase, mitochondrial
Target Involvement
Isolated sulfite oxidase deficiency (ISOD)
Target Subcellular Location
Mitochondrion intermembrane space.
Target Research Area
Metabolism
Target Synonyms
EC 1.8.3.1; mitochondrial; Sulfite oxidase; Sulfite oxidase mitochondrial ; Sulfite oxidase; mitochondrial precursor; Suox; SUOX_HUMAN
Target Background
Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins.
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