Recombinant Human Synaptobrevin homolog YKT6 (YKT6)

Uniprot Id

O15498

Target Species

Human

Target Name

YKT6

Target Full Name

Synaptobrevin homolog YKT6

Target Function

Vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. Functions in endoplasmic reticulum to Golgi transport; as part of a SNARE complex composed of GOSR1, GOSR2 and STX5. Functions in early/recycling endosome to TGN transport; as part of a SNARE complex composed of BET1L, GOSR1 and STX5. Has a S-palmitoyl transferase activity.

Target Subcellular Location

Cytoplasm, cytosol. Cytoplasmic vesicle membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Note=Probably cycles through vesicles between Golgi and endosomes.

Target Protein Families

Synaptobrevin family

Target Synonyms

R SNARE; SNARE protein Ykt6; Synaptobrevin homolog YKT6; YKT 6; YKT6; YKT6 S. cerevisiae homolog of; YKT6 v SNARE homolog; YKT6 v SNARE protein; YKT6_HUMAN

Target Background

This gene product is one of the SNARE recognition molecules implicated in vesicular transport between secretory compartments. It is a membrane associated, isoprenylated protein that functions at the endoplasmic reticulum-Golgi transport step. This protein is highly conserved from yeast to human and can functionally complement the loss of the yeast homolog in the yeast secretory pathway.