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| Cat.No | ACP08677 | Target Name | SNPH |
|---|---|---|---|
| Target Synonyms | bA314N13.5; KIAA0374; Snph; SNPH_HUMAN; Syntaphilin | Form | Liquid or Lyophilized powder |
| Expression System | Mammalian cell | Protein Length | Partial |
| Purity | >85% (SDS-PAGE)(SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O15079 |
|---|
Uniprot Id
O15079
Target Species
Human
Target Name
SNPH
Target Full Name
Syntaphilin
Target Function
Inhibits SNARE complex formation by absorbing free syntaxin-1.
Target Subcellular Location
Membrane; Single-pass membrane protein. Cell junction, synapse, synaptosome.
Target Tissue Specificity
Brain specific. Found in synapses.
Target Research Area
Neuroscience
Target Synonyms
bA314N13.5; KIAA0374; Snph; SNPH_HUMAN; Syntaphilin
Target Background
Syntaxin-1, synaptobrevin/VAMP, and SNAP25 interact to form the SNARE complex, which is required for synaptic vesicle docking and fusion. The protein encoded by this gene is membrane-associated and inhibits SNARE complex formation by binding free syntaxin-1. Expression of this gene appears to be brain-specific. Alternative splicing results in multiple transcript variants encoding different isoforms.
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