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| Cat.No | ACP21760 | Target Name | STXBP3 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-592 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O00186 |
|---|
Uniprot Id
O00186
Target Species
Human
Target Name
STXBP3
Target Full Name
Syntaxin-binding protein 3
Target Function
Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.
Target Subcellular Location
Cytoplasm, cytosol. Cell membrane. Note=In platelets, predominantly cytosolic. Low amounts membrane-associated.
Target Protein Families
STXBP/unc-18/SEC1 family
Target Tissue Specificity
Megakaryocytes and platelets.
Target Synonyms
Munc18 3; Munc18 c; Platelet Sec1 protein; Protein unc-18 homolog 3; Protein unc-18 homolog C; PSP; STXB3_HUMAN; STXBP 3; STXBP3; Sxtbp3; syntaxin 4 binding protein; Syntaxin binding protein 3; Syntaxin-binding protein 3; Unc 18 3; Unc 18 homolog 3; Unc 18c; Unc-18C; Unc18-3
Target Background
Enables syntaxin binding activity. Involved in negative regulation of calcium ion-dependent exocytosis; neutrophil degranulation; and platelet aggregation. Located in cytosol; plasma membrane; and secretory granule. Is active in presynapse.
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