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Recombinant Human Syntaxin-binding protein 4 (STXBP4)

ACP15949

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP15949 Target NameSTXBP4
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-553Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ6ZWJ1
Background Information
  • Uniprot Id

    Q6ZWJ1

  • Target Species

    Human

  • Target Name

    STXBP4

  • Target Full Name

    Syntaxin-binding protein 4

  • Target Function

    Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.

  • Target Subcellular Location

    Cytoplasm.

  • Target Synonyms

    FLJ16496; MGC149829; MGC50337; OTTHUMP00000082667; OTTHUMP00000227400; STX4-interacting protein; STXB4_HUMAN; Stxbp4; Synip; Syntaxin 4 interacting protein; Syntaxin 4-interacting protein; Syntaxin binding protein 4; Syntaxin-binding protein 4

  • Target Background

    Enables syntaxin binding activity. Involved in several processes, including positive regulation of cell cycle G1/S phase transition; positive regulation of keratinocyte proliferation; and protein stabilization. Located in extracellular exosome.

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