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| Cat.No | ACP09497 | Target Name | TBX22 |
|---|---|---|---|
| Target Synonyms | TBX22; TBOX22; T-box transcription factor TBX22; T-box protein 22 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-520 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9Y458 |
|---|
Uniprot Id
Q9Y458
Target Species
Human
Target Name
TBX22
Target Full Name
T-box transcription factor TBX22
Target Function
Probable transcriptional regulator involved in developmental processes. This is major determinant crucial to palatogenesis.
Target Involvement
Cleft palate with or without ankyloglossia, X-linked (CPX); Abruzzo-Erickson syndrome (ABERS)
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Seems to be expressed at a low level.
Target Synonyms
TBX22; TBOX22; T-box transcription factor TBX22; T-box protein 22
Target Background
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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