Recombinant Human T-cell leukemia translocation-altered gene protein (TCTA)

ACP22759

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Specifications

Cat.No	ACP22759	Target Name	TCTA
Target Synonyms	T-cell leukemia translocation altered gene; T-cell leukemia translocation-altered gene protein; T-cell leukemia translocation-associated gene protein; Tcta; TCTA_HUMAN	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-103
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P57738

Background Information

Uniprot Id

P57738
Target Species

Human
Target Name

TCTA
Target Full Name

T-cell leukemia translocation-altered gene protein
Target Function

May be required for cellular fusion during osteoclastogenesis.
Target Involvement

A chromosomal aberration involving TCTA is associated with T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(1;3)(p34;p21).
Target Subcellular Location

Membrane; Multi-pass membrane protein.
Target Protein Families

TCTA family
Target Tissue Specificity

Ubiquitous. Highest level of expression in kidney. Present in monocytes, osteoclasts, macrophages, synoviocytes and synovial lining cells (at protein level).
Target Synonyms

T-cell leukemia translocation altered gene; T-cell leukemia translocation-altered gene protein; T-cell leukemia translocation-associated gene protein; Tcta; TCTA_HUMAN
Target Background

Involved in negative regulation of osteoclast differentiation and osteoclast fusion. Predicted to be integral component of membrane.

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Recombinant Human T-cell leukemia translocation-altered gene protein (TCTA)

Specifications

Immunogen Information

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