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Recombinant Human T-lymphocyte activation antigen CD80 (CD80), Truncated

ACP02502

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Specifications

Cat.No	ACP02502	Target Name	CD80
Target Synonyms	CD80; CD28LG; CD28LG1; LAB7; T-lymphocyte activation antigen CD80; Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD antigen CD80	Form	Liquid or Lyophilized powder
Expression System	Mammalian cell	Expression Range	35-242aa
Mol Weight	51.4 kDa	Protein Length	Extracellular Domain
Purity	Greater than 85% as determined by SDS-PAGE.	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P33681

Background Information

Uniprot Id

P33681
Target Species

Human
Target Name

CD80
Target Full Name

T-lymphocyte activation antigen CD80
Target Function

Involved in the costimulatory signal essential for T-lymphocyte activation. T-cell proliferation and cytokine production is induced by the binding of CD28, binding to CTLA-4 has opposite effects and inhibits T-cell activation.; (Microbial infection) Acts as a receptor for adenovirus subgroup B.
Target Subcellular Location

Membrane; Single-pass type I membrane protein.
Target Tissue Specificity

Expressed on activated B-cells, macrophages and dendritic cells.
Target Research Area

Immunology
Target Synonyms

CD80; CD28LG; CD28LG1; LAB7; T-lymphocyte activation antigen CD80; Activation B7-1 antigen; BB1; CTLA-4 counter-receptor B7.1; B7; CD antigen CD80
Target Background

The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy.

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Recombinant Human T-lymphocyte activation antigen CD80 (CD80), Truncated

Specifications

Immunogen Information

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