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| Cat.No | ACP15568 | Target Name | TAC4 |
|---|---|---|---|
| Target Synonyms | TAC4; Tachykinin-4; Preprotachykinin-C; PPT-C) [Cleaved into: Endokinin-A; EKA); Endokinin-A/B; EKA/B); Endokinin-C; EKC)] | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 21-67 |
| Protein Length | Cytoplasmic Domain | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q86UU9 |
|---|
Uniprot Id
Q86UU9
Target Species
Human
Target Name
TAC4
Target Full Name
Tachykinin-4
Target Function
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Endokinin-A induces thermal hyperalgesia and pain-related behavior such as scratching following intrathecal administration in rats. These effects are suppressed by treatment with endokinin-C. Endokinin-A/B reduces arterial blood pressure and increases sperm motility.
Target Subcellular Location
Secreted.
Target Protein Families
Tachykinin family
Target Tissue Specificity
Expressed at low levels in the uterus of both pregnant and non-pregnant women. Isoform 1 is found only in the adrenal gland and fetal liver. Isoform 2 is found in heart, liver, bone marrow, prostate, adrenal gland and testis. Isoform 3 and isoform 4 are e
Target Synonyms
TAC4; Tachykinin-4; Preprotachykinin-C; PPT-C) [Cleaved into: Endokinin-A; EKA); Endokinin-A/B; EKA/B); Endokinin-C; EKC)]
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