Recombinant Human Taste receptor type 2 member 10 (TAS2R10), Truncated

Uniprot Id

Q9NYW0

Target Species

Human

Target Name

TAS2R10

Target Full Name

Taste receptor type 2 member 10

Target Function

Gustducin-coupled strychnine receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.

Target Subcellular Location

Membrane; Multi-pass membrane protein.

Target Protein Families

G-protein coupled receptor T2R family

Target Tissue Specificity

Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.

Target Research Area

Others

Target Synonyms

TAS2R10; Taste receptor type 2 member 10; T2R10; Taste receptor family B member 2; TRB2

Target Background

This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.