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Recombinant Human Testisin (PRSS21)

ACP03125

Number
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Specifications


Cat.No ACP03125 Target NamePRSS21
Target SynonymsEosinophil serine protease 1; ESP-1; ESP1 ; Prss21; Serine protease 21; TEST_HUMAN; TEST1; TestisinFormLiquid or Lyophilized powder
Expression SystemMammalian cellExpression Range42-288aa
Mol Weight31.8kDaProtein LengthFull Length of Mature Protein
PurityGreater than 90% as determined by SDS-PAGE.Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9Y6M0
Background Information
  • Uniprot Id

    Q9Y6M0

  • Target Species

    Human

  • Target Name

    PRSS21

  • Target Full Name

    Testisin

  • Target Function

    Could regulate proteolytic events associated with testicular germ cell maturation.

  • Target Subcellular Location

    Cell membrane; Lipid-anchor, GPI-anchor.

  • Target Protein Families

    Peptidase S1 family

  • Target Tissue Specificity

    Expressed predominantly in premeiotic testicular germ cells, mostly late pachytene and diplotene spermatocytes.

  • Target Research Area

    Cancer

  • Target Synonyms

    Eosinophil serine protease 1; ESP-1; ESP1 ; Prss21; Serine protease 21; TEST_HUMAN; TEST1; Testisin

  • Target Background

    This gene encodes a cell-surface anchored serine protease, which is a member of the trypsin family of serine proteases. The encoded protein is predicted to be active on peptide linkages involving the carboxyl group of lysine or arginine. The encoded protein localizes to the cytoplasm and the plasma membrane of premeiotic testicular germ cells and may be involved in progression of testicular tumors of germ cell origin. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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