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| Cat.No | ACP06624 | Target Name | TSPAN15 |
|---|---|---|---|
| Target Synonyms | TSPAN15; NET7; TM4SF15; UNQ677/PRO1311; Tetraspanin-15; Tspan-15; Tetraspan NET-7; Transmembrane 4 superfamily member 15 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O95858 |
|---|
Uniprot Id
O95858
Target Species
Human
Target Name
TSPAN15
Target Full Name
Tetraspanin-15
Target Function
Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10. Promotes ADAM10-mediated cleavage of CDH2. Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Late endosome membrane.
Target Protein Families
Tetraspanin (TM4SF) family
Target Synonyms
TSPAN15; NET7; TM4SF15; UNQ677/PRO1311; Tetraspanin-15; Tspan-15; Tetraspan NET-7; Transmembrane 4 superfamily member 15
Target Background
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene.
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