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| Cat.No | ACP14625 | Target Name | TTC5 |
|---|---|---|---|
| Target Synonyms | TTC5Tetratricopeptide repeat protein 5; TPR repeat protein 5; Stress-responsive activator of p300; Strap | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-440 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8N0Z6 |
|---|
Uniprot Id
Q8N0Z6
Target Species
Human
Target Name
TTC5
Target Full Name
Tetratricopeptide repeat protein 5
Target Function
Adapter protein involved in p53/TP53 response that acts by regulating and mediating the assembly of multi-protein complexes. Required to facilitate the interaction between JMY and p300/EP300 and increase p53/TP53-dependent transcription and apoptosis. Prevents p53/TP53 degradation by MDM2.
Target Subcellular Location
Nucleus. Cytoplasm.
Target Synonyms
TTC5Tetratricopeptide repeat protein 5; TPR repeat protein 5; Stress-responsive activator of p300; Strap
Target Background
Predicted to enable DNA binding activity and chromatin binding activity. Predicted to be involved in DNA repair. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Located in nucleoplasm.
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