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| Cat.No | ACP13873 | Target Name | THAP4 |
|---|---|---|---|
| Target Synonyms | THAP4; CGI-36; PP238; THAP domain-containing protein 4 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-577 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8WY91 |
|---|
Uniprot Id
Q8WY91
Target Species
Human
Target Name
THAP4
Target Full Name
Peroxynitrite isomerase THAP4
Target Function
Heme-binding protein able to scavenge peroxynitrite and to protect free L-tyrosine against peroxynitrite-mediated nitration, by acting as a peroxynitrite isomerase that converts peroxynitrite to nitrate. Therefore, this protein likely plays a role in peroxynitrite sensing and in the detoxification of reactive nitrogen and oxygen species (RNS and ROS, respectively). Is able to bind nitric oxide (NO) in vitro, but may act as a sensor of peroxynitrite levels in vivo, possibly modulating the transcriptional activity residing in the N-terminal region.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Synonyms
THAP4; CGI-36; PP238; THAP domain-containing protein 4
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