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Recombinant Human Thiamin pyrophosphokinase 1 (TPK1)

ACP03375

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Specifications

Cat.No	ACP03375	Target Name	TPK1
Target Synonyms	hTPK1; Placental protein 20; PP20; Thiamin pyrophosphokinase 1; Thiamine diphosphokinase; Thiamine kinase; Thiamine pyrophosphokinase 1; THMD5; TPK1; TPK1_HUMAN	Form	Liquid or Lyophilized powder
Expression System	E.coli	Expression Range	1-243aa
Mol Weight	54.3kDa	Protein Length	Full length
Purity	Greater than 90% as determined by SDS-PAGE.	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9H3S4

Background Information

Uniprot Id

Q9H3S4
Target Species

Human
Target Name

TPK1
Target Full Name

Thiamine pyrophosphokinase 1
Target Function

Catalyzes the phosphorylation of thiamine to thiamine pyrophosphate. Can also catalyze the phosphorylation of pyrithiamine to pyrithiamine pyrophosphate.
Target Involvement

Thiamine metabolism dysfunction syndrome 5, episodic encephalopathy type (THMD5)
Target Protein Families

Thiamine pyrophosphokinase family
Target Tissue Specificity

Detected in heart, kidney, testis, small intestine and peripheral blood leukocytes, and at very low levels in a variety of tissues.
Target Research Area

others
Target Synonyms

hTPK1; Placental protein 20; PP20; Thiamin pyrophosphokinase 1; Thiamine diphosphokinase; Thiamine kinase; Thiamine pyrophosphokinase 1; THMD5; TPK1; TPK1_HUMAN
Target Background

The protein encoded by this gene functions as a homodimer and catalyzes the conversion of thiamine to thiamine pyrophosphate, a cofactor for some enzymes of the glycolytic and energy production pathways. Defects in this gene are a cause of thiamine metabolism dysfunction syndrome-5.

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Recombinant Human Thiamin pyrophosphokinase 1 (TPK1)

Specifications

Immunogen Information

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