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| Cat.No | ACP18000 | Target Name | TST |
|---|---|---|---|
| Target Synonyms | GlpE; RDS; Rhodanese; Thiosulfate sulfurtransferase; Thiosulfate sulfurtransferase GlpE; THTR_HUMAN; TST | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 2-297 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q16762 |
|---|
Uniprot Id
Q16762
Target Species
Human
Target Name
TST
Target Full Name
Thiosulfate sulfurtransferase
Target Function
Formation of iron-sulfur complexes, cyanide detoxification or modification of sulfur-containing enzymes. Other thiol compounds, besides cyanide, can act as sulfur ion acceptors. Also has weak mercaptopyruvate sulfurtransferase (MST) activity. Together with MRPL18, acts as a mitochondrial import factor for the cytosolic 5S rRNA. Only the nascent unfolded cytoplasmic form is able to bind to the 5S rRNA.
Target Subcellular Location
Mitochondrion matrix.
Target Synonyms
GlpE; RDS; Rhodanese; Thiosulfate sulfurtransferase; Thiosulfate sulfurtransferase GlpE; THTR_HUMAN; TST
Target Background
This is one of two neighboring genes encoding similar proteins that each contain two rhodanese domains. The encoded protein is localized to the mitochondria and catalyzes the conversion of thiosulfate and cyanide to thiocyanate and sulfite. In addition, the protein interacts with 5S ribosomal RNA and facilitates its import into the mitochondria. Alternative splicing results in multiple transcript variants.
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