Recombinant Human THO complex subunit 7 homolog (THOC7)

Cat.No	ACP16381	Target Name	THOC7
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Expression Range	2-204	Protein Length	Full Length of Mature Protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP16381

Target Name

THOC7

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Expression Range

2-204

Protein Length

Full Length of Mature Protein

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	Q6I9Y2

Background Information

Uniprot Id

Q6I9Y2
Target Species

Human
Target Name

THOC7
Target Full Name

THO complex subunit 7
Target Function

Required for efficient export of polyadenylated RNA. Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway.; The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production.
Target Subcellular Location

Cytoplasm. Nucleus. Nucleus speckle.
Target Protein Families

THOC7 family
Target Synonyms

FLJ23445; fSAP24; Functional spliceosome associated protein 24; Functional spliceosome-associated protein 24; hTREX30; Ngg1 interacting factor 3 like 1 binding protein 1; Ngg1 interacting factor 3 like protein 1 binding protein 1; Ngg1-interacting factor 3-like protein 1-binding protein 1; NIF3L1 binding protein 1; NIF3L1-binding protein 1; NIF3L1BP1; THO complex 7 homolog (Drosophila); THO complex 7 homolog; THO complex subunit 7 homolog; THOC 7; thoc7; THOC7_HUMAN
Target Background

Predicted to enable RNA binding activity. Involved in mRNA export from nucleus and viral mRNA export from host cell nucleus. Located in cytosol and nuclear speck. Part of THO complex part of transcription export complex. Colocalizes with chromosome, telomeric region.

Recombinant Human THO complex subunit 7 homolog (THOC7)

Specifications

Immunogen Information

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