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| Cat.No | ACP23849 | Target Name | TARS |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-723 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P26639 |
|---|
Uniprot Id
P26639
Target Species
Human
Target Name
TARS
Target Full Name
Threonine--tRNA ligase 1, cytoplasmic
Target Function
Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction: threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged tRNA(Thr) via its editing domain, at the post-transfer stage.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Class-II aminoacyl-tRNA synthetase family
Target Synonyms
cytoplasmic; MGC9344; SYTC_HUMAN; TARS; Threonine tRNA ligase 1; Threonine tRNA ligase 1; cytoplasmic; Threonine--tRNA ligase; Threonyl tRNA synthetase; Threonyl tRNA synthetase; cytoplasmic; Threonyl-tRNA synthetase; ThrRS
Target Background
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Threonyl-tRNA synthetase belongs to the class-II aminoacyl-tRNA synthetase family
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