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Recombinant Human Thyroid receptor-interacting protein 6 (TRIP6)

ACP18017

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP18017 Target NameTRIP6
FormLyophilized powderExpression SystemCustom Production. Please inquire and provide the desire expression system.
Expression Range1-476Protein LengthFull length protein
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ15654
Background Information
  • Uniprot Id

    Q15654

  • Target Species

    Human

  • Target Name

    TRIP6

  • Target Full Name

    Thyroid receptor-interacting protein 6

  • Target Function

    Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor.

  • Target Subcellular Location

    Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Nucleus. Cytoplasm.

  • Target Protein Families

    Zyxin/ajuba family

  • Target Tissue Specificity

    Abundantly expressed in kidney, liver and lung. Lower levels in heart, placenta and pancreas. Expressed in colonic epithelial cells. Up-regulated in colonic tumors.

  • Target Synonyms

    MGC10556; MGC10558; MGC29959; MGC3837; MGC4423; OIP-1; OIP1; OPA interacting protein 1; OPA-interacting protein 1; Thyroid hormone receptor interactor 6; Thyroid receptor interacting protein 6; Thyroid receptor-interacting protein 6; TR-interacting protein 6; TRIP-6; Trip6; TRIP6_HUMAN; TRIP6i2; ZRP 1; ZRP-1; Zyxin-related protein 1

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