-
Chinese (Simplified)
-
English
-
German
-
Korean
-
Spanish
Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
| Cat.No | ACP18017 | Target Name | TRIP6 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-476 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q15654 |
|---|
Uniprot Id
Q15654
Target Species
Human
Target Name
TRIP6
Target Full Name
Thyroid receptor-interacting protein 6
Target Function
Relays signals from the cell surface to the nucleus to weaken adherens junction and promote actin cytoskeleton reorganization and cell invasiveness. Involved in lysophosphatidic acid-induced cell adhesion and migration. Acts as a transcriptional coactivator for NF-kappa-B and JUN, and mediates the transrepression of these transcription factors induced by glucocorticoid receptor.
Target Subcellular Location
Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Nucleus. Cytoplasm.
Target Protein Families
Zyxin/ajuba family
Target Tissue Specificity
Abundantly expressed in kidney, liver and lung. Lower levels in heart, placenta and pancreas. Expressed in colonic epithelial cells. Up-regulated in colonic tumors.
Target Synonyms
MGC10556; MGC10558; MGC29959; MGC3837; MGC4423; OIP-1; OIP1; OPA interacting protein 1; OPA-interacting protein 1; Thyroid hormone receptor interactor 6; Thyroid receptor interacting protein 6; Thyroid receptor-interacting protein 6; TR-interacting protein 6; TRIP-6; Trip6; TRIP6_HUMAN; TRIP6i2; ZRP 1; ZRP-1; Zyxin-related protein 1
Notification