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Recombinant Human Transcription factor SOX-3 (SOX3)

ACP23300

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Specifications

Cat.No	ACP23300	Target Name	SOX3
Target Synonyms	GHDX; MRGH; PHP; PHPX; sox3; SOX3_HUMAN; SOXB; SRY (sex determining region Y)-box 3; SRY Box 3; SRY-related HMG-box gene 3; Transcription factor Sox-3	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-446
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P41225

Background Information

Uniprot Id

P41225
Target Species

Human
Target Name

SOX3
Target Full Name

Transcription factor SOX-3
Target Function

Transcription factor required during the formation of the hypothalamo-pituitary axis. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. Required also within the pharyngeal epithelia for craniofacial morphogenesis. Controls a genetic switch in male development. Is necessary for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells.
Target Involvement

Panhypopituitarism X-linked (PHPX); Mental retardation, X-linked, with isolated growth hormone deficiency (MRXGH); 46,XX sex reversal 3 (SRXX3)
Target Subcellular Location

Nucleus.
Target Synonyms

GHDX; MRGH; PHP; PHPX; sox3; SOX3_HUMAN; SOXB; SRY (sex determining region Y)-box 3; SRY Box 3; SRY-related HMG-box gene 3; Transcription factor Sox-3

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Recombinant Human Transcription factor SOX-3 (SOX3)

Specifications

Immunogen Information

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