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| Cat.No | ACP14894 | Target Name | SPIC |
|---|---|---|---|
| Target Synonyms | AU019198; C76795; MGC40611; MGC80555; Prf; Pu.1 related factor; Spi C; Spi C transcription factor; Spi-C transcription factor (Spi-1/PU.1 related); spiC; SPIC_HUMAN; Transcription factor Spi-C | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-248 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8N5J4 |
|---|
Uniprot Id
Q8N5J4
Target Species
Human
Target Name
SPIC
Target Full Name
Transcription factor Spi-C
Target Function
Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression.
Target Subcellular Location
Nucleus.
Target Protein Families
ETS family
Target Tissue Specificity
Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver.
Target Synonyms
AU019198; C76795; MGC40611; MGC80555; Prf; Pu.1 related factor; Spi C; Spi C transcription factor; Spi-C transcription factor (Spi-1/PU.1 related); spiC; SPIC_HUMAN; Transcription factor Spi-C
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