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| Cat.No | ACP13267 | Target Name | TAF4B |
|---|---|---|---|
| Target Synonyms | TAF4B; TAF2C2; TAFII105; Transcription initiation factor TFIID subunit 4B; Transcription initiation factor TFIID 105 kDa subunit; TAF(II)105; TAFII-105; TAFII105 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q92750 |
|---|
Uniprot Id
Q92750
Target Species
Human
Target Name
TAF4B
Target Full Name
Transcription initiation factor TFIID subunit 4B
Target Function
Cell type-specific subunit of the general transcription factor TFIID that may function as a gene-selective coactivator in certain cells. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. TAF4B is a transcriptional coactivator of the p65/RELA NF-kappa-B subunit. Involved in the activation of a subset of antiapoptotic genes including TNFAIP3. May be involved in regulating folliculogenesis. Through interaction with OCBA/POU2AF1, acts as a coactivator of B-cell-specific transcription. Plays a role in spermiogenesis and oogenesis.
Target Involvement
Spermatogenic failure 13 (SPGF13)
Target Subcellular Location
Nucleus. Cytoplasm.
Target Protein Families
TAF4 family
Target Tissue Specificity
Preferentially expressed in ovarian granulosa cells (at protein level). Highly expressed in B-cells.
Target Synonyms
TAF4B; TAF2C2; TAFII105; Transcription initiation factor TFIID subunit 4B; Transcription initiation factor TFIID 105 kDa subunit; TAF(II)105; TAFII-105; TAFII105
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