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| Cat.No | ACP01583 | Target Name | BACH2 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 618-770aa | Mol Weight | 23.5 kDa |
| Protein Length | Partial | Purity | Greater than 85% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BYV9 |
|---|
Uniprot Id
Q9BYV9
Target Species
Human
Target Name
BACH2
Target Full Name
Transcription regulator protein BACH2
Target Function
Transcriptional regulator that acts as repressor or activator. Binds to Maf recognition elements (MARE). Plays an important role in coordinating transcription activation and repression by MAFK. Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1. Positively regulates the nuclear import of actin. Is a key regulator of adaptive immunity, crucial for the maintenance of regulatory T-cell function and B-cell maturation.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
BZIP family, CNC subfamily
Target Tissue Specificity
B-cell specific.
Target Research Area
Cell Biology
Target Synonyms
Bach 2; Bach2; BACH2_HUMAN; Basic leucine zipper transcription factor 2; BTB and CNC homolog 2; BTB and CNC homology 1 basic leucine zipper transcription factor 2; BTB domain and CNC homolog 2; BTBD25; OTTHUMP00000016867; OTTHUMP00000016868; OTTHUMP00000040591; Transcription regulator protein BACH2
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