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Recombinant Human Transformer-2 protein homolog beta (TRA2B)

ACP05199

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Specifications

Cat.No	ACP05199	Target Name	TRA2B
Form	Liquid or Lyophilized powder	Expression System	Baculovirus
Expression Range	2-288aa	Mol Weight	37.6 kDa
Protein Length	Full Length of Mature Protein	Purity	Greater than 90% as determined by SDS-PAGE.
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P62995

Background Information

Uniprot Id

P62995
Target Species

Human
Target Name

TRA2B
Target Full Name

Transformer-2 protein homolog beta
Target Function

Sequence-specific RNA-binding protein which participates in the control of pre-mRNA splicing. Can either activate or suppress exon inclusion. Acts additively with RBMX to promote exon 7 inclusion of the survival motor neuron SMN2. Activates the splicing of MAPT/Tau exon 10. Alters pre-mRNA splicing patterns by antagonizing the effects of splicing regulators, like RBMX. Binds to the AG-rich SE2 domain in the SMN exon 7 RNA. Binds to pre-mRNA.
Target Subcellular Location

Nucleus.
Target Protein Families

Splicing factor SR family
Target Tissue Specificity

Highest expression in heart, skeletal muscle and pancreas. Less abundant in kidney, placenta and brain. Lowest expression in kidney and liver.
Target Research Area

Epigenetics and Nuclear Signaling
Target Synonyms

arginine/serine-rich 10; Arginine/serine-rich splicing factor 10; hTRA2-beta; SFRS10; Splicing factor; Splicing factor arginine/serine rich 10; SRFS10; TRA-2 beta; TRA2-beta; Tra2b; TRA2B_HUMAN; TRAN2B; Transformer 2 beta homolog; Transformer-2 protein homolog B; Transformer-2 protein homolog beta; Transformer-2-beta

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Recombinant Human Transformer-2 protein homolog beta (TRA2B)

Specifications

Immunogen Information

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