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| Cat.No | ACP05263 | Target Name | TKT |
|---|---|---|---|
| Target Synonyms | EC 2.2.1.1; FLJ34765; TK; TKT 1; tkt; TKT_HUMAN; TKT1; Transketolase (Wernicke Korsakoff syndrome); Transketolase | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-623aa |
| Mol Weight | 67.9 kDa | Protein Length | Full length |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P29401 |
|---|
Uniprot Id
P29401
Target Species
Human
Target Name
TKT
Target Full Name
Transketolase
Target Function
Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
Target Involvement
Short stature, developmental delay, and congenital heart defects (SDDHD)
Target Protein Families
Transketolase family
Target Research Area
Cardiovascular
Target Synonyms
EC 2.2.1.1; FLJ34765; TK; TKT 1; tkt; TKT_HUMAN; TKT1; Transketolase (Wernicke Korsakoff syndrome); Transketolase
Target Background
This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
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