Recombinant Human Translocon-associated protein subunit delta (SSR4), Truncated

Uniprot Id

P51571

Target Species

Human

Target Name

SSR4

Target Full Name

Translocon-associated protein subunit delta

Target Function

TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby regulate the retention of ER resident proteins.

Target Involvement

Congenital disorder of glycosylation 1Y (CDG1Y)

Target Subcellular Location

Endoplasmic reticulum membrane; Single-pass type I membrane protein.

Target Protein Families

TRAP-delta family

Target Synonyms

SSR4; TRAPD; Translocon-associated protein subunit delta; TRAP-delta; Signal sequence receptor subunit delta; SSR-delta

Target Background

This gene encodes the delta subunit of the translocon-associated protein complex which is involved in translocating proteins across the endoplasmic reticulum membrane. The encoded protein is located in the Xq28 region and is arranged in a compact head-to-head manner with the isocitrate dehydrogenase 3 (NAD+) gamma gene and both genes are driven by a CpG-embedded bidirectional promoter. Alternate splicing results in multiple transcript variants.