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| Cat.No | ACP08587 | Target Name | TMEM107 |
|---|---|---|---|
| Target Synonyms | TMEM107; DC20; UNQ638/PRO1268; Transmembrane protein 107 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6UX40 |
|---|
Uniprot Id
Q6UX40
Target Species
Human
Target Name
TMEM107
Target Full Name
Transmembrane protein 107
Target Function
Plays a role in cilia formation and embryonic patterning. Requires for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with GLI2 and GLI3 to pattern ventral and intermediate neuronal cell types. During ciliogenesis regulates the ciliary transition zone localization of some MKS complex proteins.
Target Involvement
Meckel syndrome 13 (MKS13); Orofaciodigital syndrome 16 (OFD16)
Target Subcellular Location
Membrane; Multi-pass membrane protein. Cell projection, cilium.
Target Synonyms
TMEM107; DC20; UNQ638/PRO1268; Transmembrane protein 107
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