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| Cat.No | ACP06882 | Target Name | TMEM33 |
|---|---|---|---|
| Target Synonyms | TMEM33; DB83; Transmembrane protein 33; Protein DB83; SHINC-3 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P57088 |
|---|
Uniprot Id
P57088
Target Species
Human
Target Name
TMEM33
Target Full Name
Transmembrane protein 33
Target Function
Acts as a regulator of the tubular endoplasmic reticulum (ER) network. Suppresses the RTN3/4-induced formation of the ER tubules. Positively regulates PERK-mediated and IRE1-mediated unfolded protein response signaling.
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein. Melanosome. Nucleus envelope.
Target Protein Families
PER33/POM33 family
Target Tissue Specificity
Prostate cancer and several cancer cell lines (at protein level). Widely expressed. Expressed at higher levels in endocrine-resistant breast cancer cells as compared to endocrine-sensitive breast cancer cells. Expressed at higher levels in early recurrenc
Target Synonyms
TMEM33; DB83; Transmembrane protein 33; Protein DB83; SHINC-3
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