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| Cat.No | ACP08472 | Target Name | TMEM47 |
|---|---|---|---|
| Target Synonyms | TMEM47; BCMP1; TM4SF10; Transmembrane protein 47; Brain cell membrane protein 1; Transmembrane 4 superfamily member 10 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BQJ4 |
|---|
Uniprot Id
Q9BQJ4
Target Species
Human
Target Name
TMEM47
Target Full Name
Transmembrane protein 47
Target Function
Regulates cell junction organization in epithelial cells. May play a role in the transition from adherens junction to tight junction assembly. May regulate F-actin polymerization required for tight junctional localization dynamics and affect the junctional localization of PARD6B. During podocyte differentiation may negatively regulate activity of FYN and subsequently the abundance of nephrin.
Target Subcellular Location
Membrane; Multi-pass membrane protein. Cell junction, adherens junction.
Target Protein Families
TMEM47 family
Target Tissue Specificity
Expressed in adult brain, fetal brain, cerebellum, heart, lung, prostate and thyroid.
Target Synonyms
TMEM47; BCMP1; TM4SF10; Transmembrane protein 47; Brain cell membrane protein 1; Transmembrane 4 superfamily member 10
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