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| Cat.No | ACP03974 | Target Name | TMEM98 |
|---|---|---|---|
| Target Synonyms | TMEM98; UNQ536/PRO1079; Transmembrane protein 98; Protein TADA1 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 25-226aa |
| Mol Weight | 26.2kDa | Protein Length | Full Length of Mature Protein |
| Purity | Greater than 90% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9Y2Y6 |
|---|
Uniprot Id
Q9Y2Y6
Target Species
Human
Target Name
TMEM98
Target Full Name
Transmembrane protein 98
Target Function
Functions as a negative regulator of MYRF in oligodendrocyte differentiation and myelination. Interacts with the C-terminal of MYRF inhibiting MYRF self-cleavage and N-fragment nuclear translocation. The secreted form promotes differentiation of T helper 1 cells (Th1).
Target Involvement
Nanophthalmos 4 (NNO4)
Target Subcellular Location
Cell membrane; Single-pass type II membrane protein. Secreted. Secreted, extracellular exosome. Endoplasmic reticulum membrane; Single-pass type II membrane protein.
Target Protein Families
TMEM98 family
Target Tissue Specificity
Widely expressed with high expression in the ovary, pancreas and prostate. Expressed in the eye, particularly in corneal endothelium, iris, ciliary body, sclera, optic nerve, optic nerve head, and retina. Expressed by activated peripheral blood mononuclea
Target Research Area
Cell Biology
Target Synonyms
TMEM98; UNQ536/PRO1079; Transmembrane protein 98; Protein TADA1
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