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| Cat.No | ACP08358 | Target Name | TMEM266 |
|---|---|---|---|
| Target Synonyms | TMEM266; C15orf27; HVRP1; Transmembrane protein 266; hTMEM266; HV1-related protein 1; HsHVRP1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q2M3C6 |
|---|
Uniprot Id
Q2M3C6
Target Species
Human
Target Name
TMEM266
Target Full Name
Transmembrane protein 266
Target Function
Voltage-sensor protein present on the post-synaptic side of glutamatergic mossy fibers and granule cells in the cerebellum. Despite the presence of a voltage-sensor segment, does not form a functional ion channel and its precise role remains unclear. Undergoes both rapid and slow structural rearrangements in response to changes in voltage. Contains a zinc-binding site that can regulate the slow conformational transition.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Perikaryon.
Target Tissue Specificity
Mainly expressed in the cerebellum. Also expressed in cerebral cortex, skeletal muscle and thyroid, but at much lower levels.
Target Synonyms
TMEM266; C15orf27; HVRP1; Transmembrane protein 266; hTMEM266; HV1-related protein 1; HsHVRP1
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