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| Cat.No | ACP11168 | Target Name | DUS2 |
|---|---|---|---|
| Target Synonyms | DUS2; DUS2LtRNA-dihydrouridine(20) synthase [NAD(P)+]-like; EC 1.3.1.91; Dihydrouridine synthase 2; Up-regulated in lung cancer protein 8; URLC8; tRNA-dihydrouridine synthase 2-like; hDUS2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-493 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NX74 |
|---|
Uniprot Id
Q9NX74
Target Species
Human
Target Name
DUS2
Target Full Name
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
Target Function
Dihydrouridine synthase. Catalyzes the NADPH-dependent synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR.
Target Subcellular Location
Cytoplasm. Endoplasmic reticulum. Note=Mainly at the endoplasmic reticulum.
Target Protein Families
Dus family, Dus2 subfamily
Target Tissue Specificity
Weak expression in heart, placenta and skeletal muscle. Up-regulated in most lung cancer cells (at protein level).
Target Synonyms
DUS2; DUS2LtRNA-dihydrouridine(20) synthase [NAD(P)+]-like; EC 1.3.1.91; Dihydrouridine synthase 2; Up-regulated in lung cancer protein 8; URLC8; tRNA-dihydrouridine synthase 2-like; hDUS2
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